Vitamin B12 deficiency : Vitamin B12 deficiency due to malabsorption syndrome as seen in pernicious anemia; GI pathology, dysfunction or surgery; fish tapeworm infestation; malignancy of pancreas or bowel; gluten enteropathy; sprue; small bowel bacterial overgrowth; total or partial gastrectomy; accompanying folic acid deficiency.
Increased vitamin B12 requirements: Increased vitamin B12 requirements associated with pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy and hepatic and renal disease.
Vitamin B12 absorption test : (Schilling test).Cynocobalamine (oral) is used for nutritional vitamin B12 deficiency.
Unlabeled use : Cyanocobalamine has been used to prevent and to treat cyanide toxicity associated with sodium nitroprusside. It lowers red blood cell and plasma cyanide concentrations by combing with cyanide to form cyancobalamine, which is nontoxic and excreted in the urine.
